Platelets Contain Proteins Immunologically Related to Red Cell Spectrin and Protein 4
نویسنده
چکیده
Human platelets were tested for the presence of proteins immunologically cross-reactive with red cell spectrin and protein 4.1 . As assessed by indirect immunofluorescence microscopy. platelets were specifically reactive with affinity-purified rabbit antisera against red cell spectrin and protein 4.1 . The immunoreactive platelet constituents were further analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, followed by electrophoretic transfer to nitrocellulose paper and immunoperoxidase staining. We found that whole platelets. membranes. and cytoskeletal preparations isolated by Triton X-1 00 extraction contain small amounts of proteins reacting with anti-
منابع مشابه
Platelets contain proteins immunologically related to red cell spectrin and protein 4.1.
Human platelets were tested for the presence of proteins immunologically cross-reactive with red cell spectrin and protein 4.1. As assessed by indirect immunofluorescence microscopy, platelets were specifically reactive with affinity-purified rabbit antisera against red cell spectrin and protein 4.1. The immunoreactive platelet constituents were further analyzed by sodium dodecyl sulfate-polyac...
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تاریخ انتشار 2005